Ruthenium Complexes, an Emerging Class of Leishmanicidal Drug Candidates

This review addresses the search for activity enhancement of leishmanicidal organic compounds through their coordination chemistry with ruthenium. In an introduction to leishmaniasis, its clinical manifestations, geographical distribution, available forms treatment, and challenges disease management are presented. Ruthenium complexes, owing physico-chemical biological properties, introduced as a suitable molecular library from which find alternatives current medicines. The main sections describe complexes reported in literature, organised into two groups: organometallics inorganic complexes. ruthenium is presented compared that ligands critical assessment utility future application.